Kawasaki Disease: Cardiovascular Involvement and Outcome in the British Midlands

  • Dr Abhay Bhoyar, Department of Cardiac Services, Birmingham Children’s Hospital NHS Foundation Trust, Steelhouse Lane, Birmingham B4 6NH, UK, United Kingdom
  • Dr Ashish Chikermane, Department of Cardiac Services, Birmingham Children’s Hospital NHS Foundation Trust, Steelhouse Lane, Birmingham B4 6NH, UK, United Kingdom
  • Dr Oliver Stumper, Department of Cardiac Services, Birmingham Children’s Hospital NHS Foundation Trust, Steelhouse Lane, Birmingham B4 6NH, UK, United Kingdom
  • Dr John Stckley, Department of Cardiac Services, Birmingham Children’s Hospital NHS Foundation Trust, Steelhouse Lane, Birmingham B4 6NH, UK, United Kingdom
  • Dr John Wright, Department of Cardiac Services, Birmingham Children’s Hospital NHS Foundation Trust, Steelhouse Lane, Birmingham B4 6NH, UK, United Kingdom
  • Dr Paul Miller, Department of Cardiac Services, Birmingham Children’s Hospital NHS Foundation Trust, Steelhouse Lane, Birmingham B4 6NH, UK, United Kingdom
  • Dr Joseph DeGiovanni, Department of Cardiac Services, Birmingham Children’s Hospital NHS Foundation Trust, Steelhouse Lane, Birmingham B4 6NH, UK, United Kingdom
  • Dr Rami Dhillon, Department of Cardiac Services, Birmingham Children’s Hospital NHS Foundation Trust, Steelhouse Lane, Birmingham B4 6NH, UK, United Kingdom

    • Objectives: To assess the pattern and outcome of cardiovascular (CVS) involvement in children with Kawasaki Disease (KD) as referred to the single paediatric cardiac centre in the West Midlands (WM).

    Design: Retrospective medical records analysis.

    Setting: The Cardiology Department, Birmingham Children’s Hospital, Birmingham, UK.

    Patients: 169 children with a new diagnosis of KD who underwent CVS assessment and at least a year of follow up, over a 6 year period.

    Results: Between January 2001 and December 2005, a mean of 34 children were referred annually for CVS assessment. There was CVS involvement in 18 out of 169 (10.7%) children. This comprised coronary artery abnormalities (CAA) in 16 (9.5%) children and isolated pericardial effusion in 2. Of those with CAA, 10 (5.9%) children had coronary aneurysms (CAn). Two children had giant aneurysms, of whom one experienced a myocardial infarction (MI). Moderate sized aneurysms were present in 2 and 6 children had small aneurysms. Mild dilatation of the coronary arteries without CAn was present in 6 children. There was complete resolution of CVS involvement in 14 of 18 (78%) children. There was no mortality.