Pregnancy and childbirth in patients (P) with congenital heart defects (CHD) leads to cardiologic complications (CC). The aim of the study is to evaluate frequency of CC in pregnants with CHD. Material and methods: from 2003-2008 we followed-up course of 232 pregnancies in 194 females aged 19-43 years (27,2±5,1) in tertiary center. 134P underwent surgery. 102P presented shunts defects (ASD/operated ASD, VSD/operated VSD, operated CAVC), 37P- dominant left ventricular leasions (operated aortic coarctation, operated/unoperated aortic stenosis and/or insufficiency, Marfan), 38P- dominant right ventricle anomalies and single ventricle (operated ToF, operated DORV, Ebstein, TGA-Senning, CCTGA, Eisenmenger, postFontan operation, operated truncus arteriosus), 7P– mechanical valve prosthesis, 48P– defects without hemodynamic significance (operated PDA, BAV, operated pulmonary venous connection anomaly). CC in pregnancy: deterioration of cardiac function (HF)– increase NYHA class of al least one functional class, supraventricular arrhythmia (SVA): paroxysmal supraventricular tachycardia or/and atrial fibrillation/flutter, ventricular arrhythmia (VA)≥30/h. Comparing multiple proportion determined differences in frequency of CC between analysed subgroups. Results: Death was not observed. HF was found in 28P (12,1%), VA in 15P (6,5%), SVA in 20P (8,6%). HF occurred significantly more often in P with right heart defects and single ventricle (p<0,01) in comparison to every other group of P. Analysis of frequency occurrence of VA and SVA did not reveal any significant differences between subgroups.
Conclusions: 1/Pregnancy in P with CHD followed-up by specialized cardiologists and obstetricians is safe. 2/The most frequent complication is deterioration of HF observed especially in P with right heart defects and single ventricle.