Kawasaki disease (KD) is one of the most frequently seen causes of vasculitis in childhood. Echocardiographic studies reported coronary artery dilatation with 40% prevalence.
Objective: To evaluate clinical and laboratory findings, and follow-up outcomes of 14 cases diagnosed for KD.
Material and Method: Fourteen children treated with KD were evaluated retrospectively. CBC, ESR,urinalysis, hepatic transaminases, CRP and echocardiography were performed in all patients. All patients received IVIG and ASA.
Results: Mean ages were 3.9±2.7 (9 months-8 years) years. Six (42.8%) of the patients were girls and eight (57.1%) were boys. Mean duration of the disease was 9.7 ± 4.7 (5-19) days. Nine (64.3%) patients were diagnosed at acute stage, and five (35.7%) at subacute stage. All patients had fever. Other most frequently seen findings were lymphadenopathy (57%), rash (50%), and pyuria (42%), respectively. Conjunctivitis (14.3%) and oral mucosa changes (7.1%) were observed less frequently. Baseline acute phase reactants and platelet count were significantly high. Coronary involvement was found in nine (63.4%) patients and pericardial effusions in two (14.3%) patients. There were aneurism in three (33.3%) of the patients with coronary involvement, ectasia in four (44.3%), and perivascular brightness in two (22.4%). Coronary aneurism remained in only two patients under one year of age.
Conclusions: In our patients with KD cardiac involvement was the second most associated finding. Although lacking of other major criterion of KD the children with prolonged fever must be evaluated with echocardiography. Early echocardiographic evaluation is crucial in this disease in terms of preventing severe cardiovascular complications.