Modifications in surgical technique and protocol improve Norwood outcomes in a low volume institution

  • Dr Janeth Ejike, Loma Linda Univeristy Children's Hospital, United States
  • Jennifier Newcombe, Loma Linda Univeristy Children's Hospital, United States
  • Sarah Heinonen, Loma Linda Univeristy Children's Hospital, United States
  • Corey Fuller, School of Medicine, Loma Linda University, United States
  • Dr Neda Mulla, Loma Linda Univeristy Children's Hospital, United States
  • James Fitts, United States
  • Dr Leonard Bailey, Loma Linda Univeristy Children's Hospital, United States
  • Dr Anees Razzouk, Loma Linda Univeristy Children's Hospital, United States
  • Background: Low volume institutions (<16 cases per year) may produce less favorable outcomes of the Staged Norwood procedure using Blalock Taussig shunt (BT) or right ventricle to pulmonary conduit (Sano).

    Objectives: To compare Norwood BT/Sano outcomes after implementing a protocol in a single institution.

    Methods: A retrospective review of all patients having staged Norwood BT/Sano reconstruction for **HLHS or its variants from 2002–2008. Modifications in the protocol included surgical techniques, post-operative care and follow-up surveillance.

    Results: From 2002-2004, 48.3% had the Norwood/Sano procedure compared to 54.5% in 2005-2008 (p=0.600). Modified interventions resulted in improvements in 48-hr and 30-day mortality, and survival to Stage II Glenn procedure. Age at death between groups did not reach statistical significance (p=0.385).

    Conclusions: Implementation of a multidisciplinary protocol improved survival to Stage II Glenn in patients undergoing the Norwood BT/Sano operation in a low volume institution.

    2002 – 2004 Median (range) n=29 2005-2008 Median (range) n=44 P value
    Demographics Age (days)/weight (Kg) at Norwood 8(1-64)/3.3(2-4.4) 9(3-55)/3.1(2-4.5) 0.138/0.217
    Intervention # of follow-up phone calls 0.0 (0-9) 6.0 (0-23) *<0.001
    # of outpatient appointments ƒ4.69 (6.11) ƒ9.05 (5.62) *0.003
    # of readmissions 1.0 (0-10) 2.0 (0-6) *0.010
    Pre-stage II Glenn catheterization age (months) 5.05 (2.2-10.8) 5.3 (1.5-7.4) 0.706
    Age at stage II Glenn (months) 6.5 (4.4-11.7) 6.25 (4.2-8.7) 0.886
    Norwood BT/Sano outcomes 48-hr/30-day Mortality (%) 27.6/31.0 4.5/4.5 *0.005/*0.002
    Survival to Stage II Glenn (%) 39.0 83.0 *<0.001