The number of grown-up patients with congenital heart disease (GUCH) is constantly increasing. Re-cardiac surgery in the same group is also increasing. We evaluated the problem of GUCH who underwent re-cardiac surgery. Between February 2002 and December 2008, 13 patients were performed re-cardiac surgery in Hirosaki University Hospital. There were 7 male and 6 female, and mean age were 37.6±11.2 years old. Diagnosis of congenital heart disease were as follows; Atrial septal defect (ASD) 2, ASD+mitral regurgitation 1, ASD+ventricular septal defect (VSD) 1, VSD 4, Tetralogy of Fallot (TOF) 1, Congenital aortic valve stenosis 1, Coarctation of the aorta (CoA) +VSD 1, Patent ductus arteriosus (PDA) 1, Double outlet right ventricle (DORV) 1. The reasons for re-operation were divided by related disease and acquired heart disease. Five cases were required repair of residual defects after correction. Three cases were needed replacement of valve failure after valve plasty. Two cases (TOF and CoA) were presenting for expected reoperations after correction in childhood. Two cases were required another surgery because of developing Stanfotd type A of acute aortic dissection. The case of DORV was presenting for functional repair after palliative surgery. Although all cases were successfully repaired and uneventfully discharged, residual ASD or VSD might be avoided at the first surgery. First corrective surgery with subclavian flap method was failed in CoA case. It is important to perform corrective surgery for simple cardiac anomaly for the first time and necessary to manage and follow up all patients’ life in GUCH.